Is there a link between Apigenin and Cancer?

Hot Health
By Hot Health February 1, 2017 09:42
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Is there a link between Apigenin and Cancer?

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The Incredible Health Benefits of Apigenin – Does It Really Fight Cancer?

Apigenin is a an interesting vegetable extract, a natural phytochemical, with many useful properties, which most people may not as yet be aware of.  It is found in fruits, vegetables, herbs and spices.

Apigenin is talked about widely in the scientific community because it is one of the most powerful flavonoids and is believed to fight various types of cancer, prevent heart disease and treat a number of different neurological conditions.  Apigenin is also believed to slow down aging.

This polyphenol is commonly found in vegetables like celery and parsley. It is considered to be an inexpensive nutrient that blocks several cancerous tissues from spreading through the body.

In this article, we discuss the many health benefits of Apigenin. But what fascinates us about this nutrient, more than anything else, is its ability to fight cancerous cells, assist in the destruction of cancer cells and provide protection to the cellular DNA against harmful environmental toxins that are known to result in dangerous malignancies.

Yes, this nutrient prevents cancer cells from replicating, and protects the brain cells from damage from free radicals. It also improves your cardiovascular health.

The only real issue with this nutrient is that is it not as easily available in nature in order to be mass produced. That’s why it is very difficult to get enough Apigenin from your natural diet. To get a sufficient amount of this nutrient, you might have to add Apigenin supplements to your regimen.  It is especially powerful when combined with other ingredients such as piperine, found in black pepper and dihydroxybergamottin, usually found in grapefruits.

What’s Special About Apigenin?

Apigenin is chemically referred to as a 4′, 5, 7, -trihydroxyflavone. It has been shown to fight cancers and tumors and reduce or prevent their growth within the body. This flavonoid is very effective at identifying the healthy cells from the carcinogenic cells and specifically targets the cancer cells.

This flavonoid minimizes the risk of cancer. It first locates the progression of the cancer cells and then induces apoptosis, in order to prevent the tumor from spreading to the other parts of the body. This makes this naturally occurring compound truly special.

 

Sources of Apigenin

Apigenin is found in fruits, vegetables, herbs and spices.

The most common sources of this nutrient are spices such as oregano, rosemary, thyme, coriander and basil; vegetables such as celery, artichokes, spinach and parsley.

It is also found in chamomile, lemon balm, cloves and licorice. Peppermint and red wine are other delicious sources of this nutrient.

 

Potential Anti-Cancer Properties of Apigenin

The reason many scientists rave about Apigenin is its ability to fight the harmful effects of carcinogens and fight many different cancers that cause untold damage to the body.

How does this nutrient fight cancer? Apigenin is believed to lower the risk of breast cancer, prostate cancer, stomach and bladder cancer. It also fights leukemia. This flavonoid works in many mysterious ways to mitigate the damage from free radicals and blocks COX-2.

It is a very powerful antioxidant with anti-inflammatory properties. This flavonoid strengthens the immune system by fighting back against the effects of immunosuppressants. (However, this can be dangerous for those having organ transplants.)

This flavonoid prevents or slows down the metastasis of cancerous cells, especially those that are responsible for prostate cancer or breast cancer. Let’s talk a bit more about some of the health benefits of this amazing nutrient.

 

The Amazing Health Benefits of Apigenin

  • How Apigenin fights heart disease

Apigenin relaxes the central nervous system and lowers the high blood pressure. It is one of the most potent phytochemicals occurring in nature and is considered very effective at modulating the GABA receptors present in the brain.

It has the ability to enhance StAR levels in the body. StAR is expanded as steroidogenic acute regulatory protein, which is considered essential for the creation of hormones that transport cholesterol through the body. Cholesterol is necessary for the production of critical hormones. StAR helps to supply cholesterol to the cells.  

As we enter our 30s and 40s, and resort to poor eating habits, have more alcohol than we should and fail to exercise regularly, the amount of StAR produced by the body goes down substantially.

As StAR decreases, the production of hormones slows down considerably as well. This not only accelerates the aging process, but leads to a number of different ailments, such as heart disease.

Taking Apigenin supplements may diminish the risk of clotting of the blood and boosts the production of certain hormones. It may also inhibit the production of the aromatase enzyme naturally. That’s why this flavonoid is believed to lower the risk of atherosclerosis and prevent cardiovascular diseases, including heart attack.

 

  • How does Apigenin Fight Prostate Cancer?

There are many studies that have so far done on mice in laboratory conditions that indicate that this flavonoid obstructs the growth of cancerous cells in the prostate gland. It reduces activities such as metastasis and angiogenesis, which are known to lead to cancer.  

Apigenin is particularly effective when combined with other flavonoids such as luteolin. Luteolin resists the synthesis of fatty acids, which are among the biggest causes of prostate cancer. There is still a lot of research being done on this flavonoid and its ability to prevent prostate cancer, so this is very much a developing story.  (1)

 

  • How Does Apigenin Fight Leukemia?

This flavonoid is considered to be especially effective as a natural suppressor of leukemia cells. It induces a natural apoptosis within the cells, and inhibits the progress of leukemia within the body.

Again, this is ongoing story as a lot of research is still being done on Apigenin and its ability to fight leukemia. What is clear is that this flavonoid does help patients overcome the side effects of chemotherapy during leukemia treatment.  (2)

 

  • How Apigenin Fights Gastrointestinal Cancers?

One of the wonderful health benefits of apigenin is its ability to fight gastrointestinal cancer, which is known to cause a lot of pain in patients. It does so by blocking the blood capillaries that provide fuel to the gastrointestinal tract and stopping the progression of tumor cells within the intestinal region.

This flavonoid induces a natural apoptosis within the gastrointestinal area, decreases the uptake of cellular glucose and checks the growth of the extracellular matrix. It slows down the metastatic activity around this area.

 

  • How Apigenin Fights Ovarian Cancer?

There are conflicting reports on the ability of this flavonoid at fighting ovarian cancer. The research on this is not conclusive. But there is anecdotal evidence to suggest that taking foods that are rich in Apigenin decreases the risk of ovarian cancer in women.

Of course, more research is needed before one can reach any conclusion on whether this nutrient prevents the spread of ovarian cancer or not. (3)

 

What are the Other Apigenin Health Benefits?

Apigenin is more than just an anti-carcinogenic compound. It is considered to be very effective as a mood enhancer. It is also used in some of the medications for stress, anxiety and depression.(4)

It is a powerful antioxidant, and an anti-inflammatory agent. This flavonoid fights a number of inflammatory disorders. It also reduces oxidative stress. It is a natural laxative and provides relief to the digestive system

 

What are the Side Effects of Apigenin?

There are no real Apigenin side effects as long as it is taken according to the recommended dosage. If taken naturally in the form of fruits and vegetables, there is nothing to worry about.

However, if you are going to take it in the form of supplements, you should follow your doctor’s instructions and never take more than you should. If taken in excess, this flavonoid can lead to side effects such as sedation and temporary numbness in the arms and legs.

Generally, doctors prescribe 3 to 10 mg of this flavonoid for every 1 kg of your body weight, but the dosage can vary widely and depends on the severity of your condition.

 

Final Thoughts

As said at the start, not much is known as yet about Apigenin. It is still a work in progress; a lot of research is being done it, with a special focus on its ability to prevent the progression of cancerous cells. But scientists are excited by what they have seen so far, and say that this flavonoid has very special healing powers.

Apigenin is particularly effective when combined with other flavonoids. It has very powerful anti-inflammatory properties and is used in the treatment of psychiatric disorders such anxiety and depression. It is an effective stress buster and can work as a natural laxative. What’s more, it is known to have anti-aging benefits.

 

Hot Health
By Hot Health February 1, 2017 09:42
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